The types of Porphyria are:

 

Acute Hepatic:

*ALAD Porphyria

*Acute Intermittent Porphyria

*Hereditary Coproporphyria

*Variegate Porphyria

 

Erythropoietic:

* Congential Erythropoeitic Porphyria

*Porphyria Cutanea tarda

*Hepatoerythropoeitic porphyria (inheriting PCT from both parents)

*Erythropoietic protoporphyria

*X linked Protoporphyria

There are two classifications of porphyria, they are Acute Hepatic (Liver) Porphyria or Erythropoietic (bone marrow) Porphyria. These current classifications are incomplete as there is cross over in some types.  Where heme synthesis is primarily affected in the body, in the bone marrow or in the liver, determines the symptoms that are experienced. When heme synthesis is affected in the bone marrow,the skin is primarily affected, with photo sensitivity being the most common feature. In hepatic porphyria, the nervous system is primarily affected with neuropathy — which means nerve damage — being the most common feature. Two of the acute Porphyria's, Hereditary Coproporphyria and Variegate Porphyria, and one type of Acute Intermittent Porphyria, called Chester Porphyria, may have skin issues (30 % of HCP can have skin blistering and a higher percentage of VP, however if sun exposure is limited the skin issues may be very mild in some patients), and in some patients the skin issues can be quite severe.